sampling error

Heart disease screening: where did the uncertainty go?

The UK news media have reported quite extensively a newly published paper by Wald, Simmonds and Morris on screening for cardiovascular disease (CVD) - that is, disease of the heart and blood vessels (principally heart attacks and strokes). The paper concluded that screening should be based on the patient's age alone, and not on other risk factors for CVD. But I'm not going to examine the conclusion - I'm interested in the way the authors dealt with uncertainty.

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